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appD [2018-02-13T09:02:32.000Z]
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appD [2018-02-13T09:02:32.000Z]

oligopeptide ABC transporter (ATP-binding protein)
Locus
BSU11360
Isoelectric point
5.39
Molecular weight
36.16 kDa
Protein length
328 aa Sequence Blast
Gene length
984 bp Sequence Blast
Function
uptake of oligopeptides
Product
oligopeptide ABC transporter (ATP-binding protein))
Essential
no
Synonyms

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
1,211,477 → 1,212,463

The protein

Protein family

  • ABC transporter domain (according to Swiss-Prot)
  • Paralogous protein(s)

    Structure

  • 4FWI (from Caldanaerobacter subterraneus, 38% identity) PubMed
  • Localization

  • attached to the cell membrane (via AppB-AppC) PubMed
  • Expression and Regulation

    Operons

    Description

    Regulatory mechanism

  • TnrA: activation, PubMed, in TnrA regulon
  • CodY: repression, PubMed PubMed, in CodY regulon
  • ScoC: repression, PubMed, in ScoC regulon
  • Regulation

  • repressed by CodY PubMed
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    Biological materials

    Mutant

  • GP2100 (D(appD-appF-appA/2-appB-appC)::spc), available in Jörg Stülke's lab
  • BKE11360 (ΔappD::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGCTAGCTCCCCTTTCCC, downstream forward: _UP4_GAGGAAGAGGGTGCCGAACA
  • BKK11360 (ΔappD::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGCTAGCTCCCCTTTCCC, downstream forward: _UP4_GAGGAAGAGGGTGCCGAACA
  • References

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